We are the first group that made the green fluorescent mouse in the world.

The green fluorescent protein (GFP) is responsible for the green bioluminescence of the jellyfish Aequorea victoria. Many classes of GFP mutants exist that display modified fluorescence spectra and an increased extinction coefficient. We produced transgenic mouse lines with an 'enhanced' GFP (EGFP) cDNA under the control of a chicken beta-actin promoter and cytomegalovirus enhancer. All of the tissues from these transgenic lines, with the exception of erythrocytes and hair, were green under excitation light. The fluorescent nature of the cells from these transgenic mouse lines would facilitate their use in many kinds of cell transplantation experiments

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Curr Top Dev Biol, 44,1-20 (1999)
FEBS Lett, 407, 313-9 (1997)

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• MTA Form (Acrobat Reader required)
• Green mouse lines
• Green rat
• Green ES lines
• "green mice" photos
• FACS spleen
• FACS thymus
• handy UV lamp
• Observation of GFP
• plasmid map
• plasmid sequence
• primer set
• southern blotting
• antibodies
• Health Certificate
• LINK
• List of permissions for experiments involving DNA recombination

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